MSAccess database of protecting groups
Description of ~170 protecting groups, their formation, removal
and use in organic synthesis.
Structure of the database:
The database can best be accessed as follows:
get an idea of the chemical properties of the tert-butyl group, its
compatibility with other protecting groups and conditions encountered
in synthesis one can consult the view "Properties of protecting
groups" or issue the SQL-command:
- Open table "Protection" in MSAccess and select a group you want to protect, e.g. carboxyl
- Click on the [+]-sign to open linked table "Function". Select a function e.g. ester.
- Click on the [+]-sign to open linked table "Groups". Select a group e.g. tert-butyl ester.
- Click on the [+] sign to open linked table "Methods" to view methods of formation (F) and removal (R) of the t-butyl ether. The "mode" field in table "Methods" can contain only two values: F (formation) and R (removal).
Select * from "Properties of protecting groups" where group = 't-Butyl esters';